Nothing opens

Whenever I try to open a program, I get a window "open with."  I had problems last night.  Security Center Vista kept popping up messages that I had been invaded.  When I tried to click on it, it said I had to pay to get these deleted threats.  I've already subscribed to norton 360.  I ran that, and he said that he removed two threats.  After that, I turned off the computer for the night.  Now this morning, nothing opens.  Any advice?

'Vista Security Center' is not owned by Microsoft. Your computer is infected by a rogue security program. It's called "thugs" because he pretended to be a good guy but is really bad. Don't pay them!

Run .exe from Doug Knox fix and then to clean the machine.

http://www.dougknox.com/XP/file_assoc.htm

Removal of the many variants of thugs:
http://www.bleepingcomputer.com/virus-removal/remove-antivirus-Vista-2010

These can work for you, and all can be good. However, in many cases the computer will also infected with other horses of Trojan and protected by a rootkit. These machines are extremely difficult to clean. If your machine is one of these cases, either the interactive assistance to one of the specialty forums listed in the link below, OR take your machine to a professional on the local computer OR backup your data and do a clean install of Windows. It's your choice. I do not recommend using BigComputerStore/GeekSquad types of places.

http://www.elephantboycomputers.com/page2.html#HJT-links

MS - MVP - Elephant Boy computers - don't panic!

Tags: Windows

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