After Effects CS5 stuck to the Windows 10 1511 homescreen

I had been using After Effects CS5 on Windows 10 smoothly for several weeks.  A few days ago I have upgraded to Windows 10 version 1511 (a major update), and now when I launch After Effects, the splash screen is stuck at "Initializing MediaCore."  It never makes it beyond that.  I searched and tried all the troubleshooting methods that I could find.  I have reinstalled QuickTime.  I reinstalled After Effects.  I've updated After Effects.  I have reset and delete the Preferences folder.  I have disabled the firewall.  I rebooted.  I went through the suggested troubleshooting steps.

Any suggestions or ideas on what could be the problem?  On a perhaps related note, after I updated Windows 10, I had a very strange problem a few times: when I started in Windows, the music started to come out of the speakers.  A little later, I heard static-y voice in speakers.  It was like this by the blue, no Spotify or anything I know.  My laptop picked up somehow radio waves?  Was it a bizarre kind of spyware?  Since then, I scanned with spyware.  Thanks for reading!

I found the problem after watching Process Monitor from Microsoft.  I had to uninstall Matrox codecs that I had installed quite earlier.  I tried to uninstall/reinstall Quicktime, but failed to remove the Matrox codecs.

Tags: After Effects

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