Can not stop popups and ads, have everything turned off and tried safe mode, nothing works

I found some archived topics for this particular problem and I have tried everything that has been recommended, but nothing has worked. I made sure several times all add-ons are disabled, tried in safe mode, etc. and I get these popups all over even my e-mail sites. A thread has mentioned something in your control panel, but then goes no further. Should I get something in my control panel?
Any help would be greatly appreciated.

Run most or all of the listed malware scanners. Each works differently. If a single
program forget something, someone else can pick it up.

Tags: Firefox

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