Illustrator CS5 will not honor my OS 10.8 start-up file

It took me awhile to find the startup file so I could empty all the nuances and things. So, I finally found the CMYK.ai base file. I opened it and all my changes. I saved the file and quit Illustrator. Now when I open Illustrator and create a new CMYK file took none of the changes I made for the start-up, as in all my color samples, brushes and everything like that are still there, but when I get back to the base CMYK.ai file is correct. It's the way I left it.

I illustrate illustrations for books and I don't want to have to remove all these unnecessary nuances each time I create a new file. Help, please.

Mac OS 10.8.2

Where did you go to edit the new Document profile? You want to change is in your user profile. The location varies depending on the operating system.

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