the spldr.sys file is missing!

Remember - this is a public forum so never post private information such as numbers of mail or telephone!

Get a message at startup which spldr.sys failed to load.  Have looked in System32, but it cannot see here - could it have been deleted and if so, where can I get another copy to replace it?

The spldr.sys should be there.

Please start the command prompt (cmd.exe) with admin rights [1] and run sfc [2]:

sfc.exe/scannow

He is able to find and repair broken/missing files? If this is not the case, replace the driver with the file of your DVD [3].

Best regards
André

[1] http://windows.microsoft.com/en-US/windows7/How-do-I-run-an-application-once-with-a-full-administrator-access-token
[2] http://support.microsoft.com/kb/929833
[3] http://blog.nirsoft.net/2009/09/17/how-to-extract-missing-system-files-from-the-dvd-of-windows-7vista/

"A programmer is just a tool that converts the caffeine in code" Deputy CLIP - http://www.winvistaside.de/

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